No.	Drug Name	Active Ingredient	Approval Date	FDA-approved use on approval date*	Peak Sales Forecast on Approval Date	Start Monograph
48	Ubrelvy	ubrogepant	12/23/2019	To treat acute treatment of migraine with or without aura in adults Press Release	$380MM/year	Label
47	Enhertu	fam-trastuzumab deruxtecan-nxki	12/20/2019	To treat metastatic breast cancer Press Release Drug Trials Snapshot	NA	Label
46	Dayvigo	lemborexant	12/20/2019	To treat insomnia Drug Trials Snapshot	$280MM/year	Label
45	Caplyta	lumateperone tosylate	12/20/2019	To treat schizophrenia	$210MM/year	Label
44	TissueBlue	Brilliant Blue G Ophthalmic Solution	12/20/2019	Dye used in eye surgery Drug Trials Snapshot	NA	Label
43	Padcev	enfortumab vedotin-ejfv	12/18/2019	To treat refractory bladder cancer Press Release Drug Trials Snapshot	$1,170MM/year	Label
42	Vyondys 53	golodirsen	12/12/2019	To treat certain patients with Duchenne muscular dystrophy Press Release Drug Trials Snapshot	$560MM/year	Label
41	Oxbryta	voxelotor	11/25/2019	To treat sickle cell disease Press Release Drug Trials Snapshot	$3,670MM/year	Label
40	Xcopri	cenobamate	11/21/2019	To treat partial onset seizures Press Release Drug Trials Snapshot	NA	Label
39	Givlaari	givosiran	11/20/2019	To treat acute hepatic porphyria, a rare blood disorder Press Release Drug Trials Snapshot	$890MM/year	Label
38	Adakveo	crizanlizumab-tmca	11/15/2019	To treat patients with painful complication of sickle cell disease Press Release Drug Trials Snapshot	$700MM/year	Label
37	Fetroja	cefiderocol	11/14/2019	To treat patients with complicated urinary tract infections who have limited or no alternative treatment options Press Release Drug Trials Snapshot	$140MM/year	Label
36	Brukinsa	zanubrutinib	11/14/2019	To treat certain patients with mantle cell lymphoma, a form of blood cancer Press Release Drug Trials Snapshot	NA	Label
35	Reblozyl	luspatercept–aamt	11/8/2019	For the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell transfusions Press Release Drug Trials Snapshot	NA	Label
34	ExEm Foam	air polymer-type A	11/7/2019	A diagnostic agent used to assess fallopian tube patency (openness) in women with known or suspected infertility Drug Trials Snapshot	NA	Label
33	Trikafta	elexacaftor/ivacaftor/tezacaftor	10/21/2019	To treat patients 12 years of age and older with the most common gene mutation that causes cystic fibrosis Press Release Drug Trials Snapshot	$8,290MM/year	Label
32	Reyvow	lasmiditan	10/11/2019	For the acute treatment of migraine with or without aura, in adults Press Release Drug Trials Snapshots	$600MM/year	Label
31		fluorodopa F 18	10/10/2019	A diagnostic agent for use in positron emission tomography (PET) to help diagnose adult patients with suspected Parkinsonian syndromes (PS) Drug Trials Snapshot	NA	Label
30	Scenesse	afamelanotide	10/8/2019	To increase pain-free light exposure in adult patients with a history of phototoxic reactions (damage to skin) from erythropoietic protoporphyria Press Release Drug Trials Snapshot	NA	Label
29	Beovu	brolucizumab–dbll	10/7/2019	Treatment of wet age-related macular degeneration Drug Trials Snapshot	$1,900MM/year	Label
28	Aklief	trifarotene	10/4/2019	For the topical treatment of acne vulgaris in patients 9 years of age and older Drug Trials Snapshot	NA	Label
27	Ibsrela	tenapanor	9/12/2019	To treat irritable bowel syndrome with constipation in adults. Drug Trials Snapshot	$1,090MM/year	Label
26	Nourianz	istradefylline	8/27/2019	To treat adult patients with Parkinson’s disease experiencing “off” episodes Press Release Drug Trials Snapshot	$110MM/year	Label
25	Ga-68-DOTATOC	Ga-68-DOTATOC	8/21/2019	For use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs) Drug Trials Snapshot	NA	Label
24	Xenleta	lefamulin	8/19/2019	To treat adults with community-acquired bacterial pneumonia Press Release Drug Trials Snapshot	NA	Label
23	Rinvoq	upadacitinib	8/16/2019	To treat adults with moderately to severely active rheumatoid arthritis Drug Trials Snapshot	$4,853MM/year	Label
22	Inrebic	fedratinib	8/16/2019	To treat adult patients with intermediate-2 or high-risk primary or secondary myelofibrosis Press Release Drug Trials Snapshot	$320MM/year	Label
21	Rozlytrek	entrectinib	8/15/2019	To treat adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are ROS1-positive To treat adult and pediatric patients 12 years of age and older with solid tumors Press Release Drug Trials Snapshot: Pediatric patients 12 years of age and older with solid tumors Drug Trials Snapshot: Metastatic non-small cell lung cancer (NSCLC) whose tumors are ROS1-positive	NA	Label
20	Wakix	pitolisant	8/14/2019	To treat excessive daytime sleepiness (EDS) in adult patients with narcolepsy Drug Trials Snapshot	NA	Label
19	Pretomanid	pretomanid	8/14/2019	For treatment-resistant forms of tuberculosis that affects the lungs Press Release Drug Trials Snapshot	NA	Label
18	Turalio	pexidartinib	8/2/2019	To treat adult patients with symptomatic tenosynovial giant cell tumor Press Release Drug Trials Snapshot	$80MM/year	Label
17	Nubeqa	darolutamide	7/30/2019	To treat adult patients with non-metastatic castration resistant prostate cancer Drug Trials Snapshot	$1,0209MM/year	Label
16	Accrufer	ferric maltol	7/25/2019	To treat iron deficiency anemia in adults Drug Trials Snapshot	NA	Label
15	Recarbrio	imipenem, cilastatin and relebactam	7/16/2019	To treat complicated urinary tract and complicated intra-abdominal infections Press Release Drug Trials Snapshot	NA	Label
14	Xpovio	selinexor	7/3/2019	To treat adult patients with relapsed or refractory multiple myeloma (RRMM) Press Release Drug Trials Snapshot	$610MM/year	Label
13	Vyleesi	bremelanotide	6/21/2018	To treat hypoactive sexual desire disorder in premenopausal women. Press Release Drug Trials Snapshot	NA	Label
12	Polivy	polatuzumab vedotin-piiq	6/10/2019	To treat adult patients with relapsed or refractory diffuse large B-cell lymphoma Press Release Drug Trials Snapshot	$730MM/year	Label
11	Piqray	alpelisib	5/24/2019	To treat breast cancer Press Release Drug Trials Snapshot	$1,150MM/year	Label
10	Vyndaqel	tafamidis meglumine	5/3/2019	To treat heart disease (cardiomyopathy) caused by transthyretin mediated amyloidosis (ATTR-CM) in adults Press Release Drug Trials Snapshot	$1,500MM/year	Label
9	Skyrizi	risankizumab-rzaa	4/23/2019	To treat moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy Drug Trials Snapshot	$4,800MM/year	Label
8	Balversa	erdafitinib	4/12/2019	To treat adult patients with locally advanced or metastatic bladder cancer Press Release Drug Trials Snapshot	NA	Label
7	Evenity	romosozumab-aqqg	4/9/2019	To treat osteoporosis in postmenopausal women at high risk of fracture Press Release Drug Trials Snapshot	$410MM/year	Label
6	Mayzent	siponimod	3/26/2019	To treat adults with relapsing forms of multiple sclerosis Press Release Drug Trials Snapshot	$1,600MM/year	Label
5	Sunosi	solriamfetol	3/20/2019	To treat excessive sleepiness in adult patients with narcolepsy or obstructive sleep apnea Drug Trials Snapshot	$350MM/year	Label
4	Zulresso	brexanolone	3/19/2019	To treat postpartum depression (PPD) in adult women Press Release Drug Trials Snapshot	$1,190MM/year	Label
3	Egaten	triclabendazole	2/13/2019	To treat fascioliasis, a parasitic infestation caused by two species of flatworms or trematodes that mainly the affect the liver, sometimes referred to as “liver flukes” Drug Trials Snapshot	NA	Label
2	Cablivi	caplacizumab-yhdp	2/6/2019	To treat adult patients with acquired thrombotic thrombocytopenic purpura (aTTP) Press Release Drug Trials Snapshot	NA	Label
1	Jeuveau	prabotulinumtoxinA-xvfs	2/1/2019	For the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adult patients	NA	Label

*The listed “FDA-approved use” on this website is for presentation purposes only. To see the FDA-approved conditions of use [e.g., indication(s), population(s),
dosing regimen(s)] for each of these products, see the most recent FDA-approved Prescribing Information (click on the Drug Name).